for medical use of the drug
active substance: a solution of menthol in menthyl ester of isovaleric acid;
1 capsule contains a solution of menthol in menthol ester of isovaleric acid 100 mg;
excipients: gelatin, glycerin.
Dosage form. The capsules are soft.
Main physical and chemical properties: soft gelatin capsules of spherical or spherical shape, with a seam, colorless or from pale yellow to light brownish-yellow, filled with a clear colorless or yellowish oily liquid with the smell of menthol.
Pharmacotherapeutic group. Cardiac drugs. Code ATX C01E X.
The drug has a calming effect on the central nervous system, and also has a moderate reflex vasodilating (coronary) effect by reflex stimulation of sensitive nerve ("cold") receptors of the oral mucosa. Stimulation of receptors is accompanied by induction of the release of endorphins, enkephalins, dinorphins and other peptides, histamine, kinins, which play an important role in reducing pain sensitivity, normalizing vascular permeability and regulating other important mechanisms of cardiovascular and nervous systems.
When applied sublingually, Corvalment® is absorbed from the oral mucosa. The therapeutic effect occurs after about 5 minutes.
After absorption, it is biotransformed in the liver and excreted in the urine as glucuronides.
- Mild angina attacks;
- sea and air diseases;
- Headache associated with nitrate intake.
Hypersensitivity to the components of the drug.
Severe hypotension; acute myocardial infarction.
Interaction with other medicinal products and other forms of interaction.
Corvalment® enhances the sedative effect of psychotropic drugs, opioid analgesics, alcohol and anesthetics when used simultaneously.
Potentiation of the action of antihypertensive drugs when co-administered with the drug Corvalment® is possible.
Corvalment® reduces the severity of headaches caused by the use of nitrates.
Features of application. In cases where the pain in the heart does not go away after taking the drug, it is necessary to consult a doctor to rule out acute coronary syndrome.
The drug does not contain sugar and can be used in patients with diabetes.
Use during pregnancy or breastfeeding.
The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the physician, the expected positive effect for the mother outweighs the potential risk to the fetus / child.
Ability to influence the speed of reaction when driving a car or other machinery.
Caution should be exercised in the first hours after administration of the drug when driving or operating that requires increased attention due to possible side effects (dizziness and drowsiness).
Method of application and dosage.
Keep the capsule in your mouth (under the tongue) until it is completely dissolved. To speed up the effect, you can crush the capsule with your teeth.
Single dose for adults - 1 capsule (100 mg).
The maximum daily dose is 6 capsules (600 mg).
Duration of treatment - up to 7 days.
There is no experience with the use of the drug for the treatment of children.
Symptoms: headache, nausea, agitation, heart failure, low blood pressure, central nervous system depression, hypersensitivity reactions to the components of the drug (angioneurotic edema, urticaria, itching, rash).
Treatment: drug withdrawal and symptomatic therapy.
With prolonged use, occasionally there may be mild nausea, abdominal discomfort, tearing, dizziness, short-term hypotension, drowsiness, which quickly disappear on their own.
Allergic reactions, including Quincke's edema, urticaria, rash, and pruritus, may develop.
Expiration date. 3 years.
Store in the original package at a temperature not exceeding 25 oC.
Keep out of reach of children.
Producer. JSC "KYIV VITAMIN PLANT".
Location of the manufacturer and address of the place of its activity.
04073, Ukraine, Kyiv, street Kopylivska, 38.